Subject(s)
Adult , Anti-Infective Agents/pharmacology , Bacteria/drug effects , Female , Humans , Male , Microbial Sensitivity Tests , Pyoderma/microbiologySubject(s)
Anti-Bacterial Agents/pharmacology , Bacterial Proteins , Child , Child, Preschool , Drug Resistance, Bacterial , Erythromycin/pharmacology , Humans , India/epidemiology , Membrane Proteins , Methyltransferases , Microbial Sensitivity Tests/methods , Pharynx/microbiology , Phenotype , Pyoderma/microbiology , Streptococcal Infections/microbiology , Streptococcus pyogenes/drug effectsABSTRACT
BACKGROUND: Although prevalence of MRSA strains is reported to be increasing, there are no studies of their prevalence in community-acquired primary pyodermas in western India. AIMS: This study aimed at determining the prevalence of MRSA infection in community-acquired primary pyodermas. METHODS: Open, prospective survey carried out in a tertiary care hospital in Mumbai. MATERIALS AND METHODS: Eighty-six patients with primary pyoderma, visiting the dermatology outpatient, were studied clinically and microbiologically. Sensitivity testing was done for vancomycin, sisomycin, gentamicin, framycetin, erythromycin, methicillin, cefazolin, cefuroxime, penicillin G and ciprofloxacin. Phage typing was done for MRSA positive strains. RESULTS: The culture positivity rate was 83.7%. Staphylococcus aureus was isolated in all cases except two. Barring one, all strains of Staphylococcus were sensitive to methicillin. CONCLUSIONS: Methicillin resistance is uncommon in community-acquired primary pyodermas in Mumbai. Treatment with antibacterials active against MRSA is probably unwarranted for community-acquired primary pyodermas.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Male , Methicillin Resistance , Middle Aged , Prospective Studies , Pyoderma/microbiology , Staphylococcus aureus/drug effectsABSTRACT
Staphylococcus aureus is a major pathogen for pyoderma in India. Phage pattern of bacteria gives valuable information in epidemiological studies of infection. Two hundred and two strains of Staphylococcus aureus isolated from pyoderma cases at Gorakhpur, were phage grouped and phage typed. It was found that 43.1 percent strains were not typable. Most common group was mixed phage group (23.8 percent) followed by phage group III (12.4 percent). Predominant phage types in mixed phage group was 84/81/85 and in phage group III was 84/85.
Subject(s)
Bacteriophage Typing , Humans , India , Pyoderma/microbiology , Staphylococcal Skin Infections/microbiology , Staphylococcus aureus/classificationABSTRACT
Of 100 pus samples cultured from pyodermal lesions, 99 yielded positive cultures. Staphylococcus aureus alone (45%) or with beta-haemolytic streptococci (BHS, 32%) was the commonest isolate. Antimicrobial sensitivity of 71 Staph. aureus strains tested showed high degree of resistance to erythromycin (38.3%). BHS was the second common pathogen encountered. T-agglutination patterns studied in BHS group A could type 85.7 per cent of the isolates. Non-group A BHS isolated were of group G (3) and group D (1). Five pus specimens yielded obligate anaerobes mixed with aerobes. Bacteroides melaninogenicus/asacchrolyticus was isolated in 4 of 5 samples.